Results 101 to 110 of about 1,100,534 (212)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The new shape of the student

open access: yes, 2012
This chapter critically examines student characteristics in light of the popular dis-course which describes students as part of a net generation of digital native young people. Digital and networked technologies have clearly changed the possibilities for
Jones, Chris
core  

E-Learning in Business [PDF]

open access: yes, 2004
e-Learning is replacing face-to-face classroom instruction in a growing number of businesses, but what is the prospect for the continued proliferation of e-learning in business?
Schweizer, Heidi
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Collaboration Enabling Internet Resource Collection-Building Software and Technologies [PDF]

open access: yes, 2005
Over the last decade the Library of the University of California, Riverside and its collaborators have developed a number of systems, service designs, and projects that utilize innovative technologies to foster better Internet finding tools in ...
Mitchell, Steve
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

ImpaCT2 academic report: part 4 - case study evaluations [PDF]

open access: yes, 2002
This report explored the ways in which the integration of ICT and networked technologies into the curriculum tends to produce changes in the patterns of teaching and learning.

core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

EDUCATIONAL ROBOTICS TECHNOLOGIES IN KAZAKHSTAN AND IN THE WORLD: COMPARATIVE ANALYSIS, CURRENT STATE AND PERSPECTIVES

open access: yesAstra Salvensis, 2019
Educational robotics has been evolving for quite a long time to talk about accumulated practice in the field of teaching methodologies for robotics. Some distinct directions for organizing of robotics courses have taken shape in developed countries and ...
Zhanat Kunapianovna Nurbekova   +2 more
doaj  

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