Results 61 to 70 of about 1,100,534 (212)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Novos paradigmas na educacão online com a aprendizagem aberta [PDF]
, 2007 This paper aims to discuss important concepts related to online education which bring a new educational paradigm: open learning through free learning materials and technologies.
Okada, Alexandra
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
CYCLICAL MANNER OF VEGETABLE PRODUCTION INDUSTRY; THE EFFICIENCY OF GREENHOUSE BUSINESS
Овощи России, 2017 Economical efficiency of agricultural industry is a major characteristic of the level of development of an enterprise. A profit from product sale depends on volume and structure of product sales, self-cost as well as the level of sales price ...
O. N. Krylov, O. Y. Abisheva
doaj +1 more source
AISR Connections Fall 2012 (2012-2013 Orientation Issue) [PDF]
, 2012 Yearly publication of AISR Connections for 2012-2013. Issue includes: Scott Library renovations New library catalog Clinical Resources Support Jefferson Digital Commons The mission of Academic & Instructional Support & Resources (AISR) is to ...
AISR,
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mathematical Models for the Design of GRID Systems to Solve Resource-Intensive Problems
MathematicsArtificial neural networks are successfully used to solve a wide variety of scientific and technical problems. The purpose of the study is to increase the efficiency of distributed solutions for problems involving structural-parametric synthesis of ...
Valeriya V. Tynchenko +7 more
doaj +1 more source
, 2016 I re-appropriate the image of a space-time warp and its notion of disorientation to argue that colonialism created a warp in Trinidad’s educational system. Through an analysis of school violence and the wider network of structural violence in which it is
Williams, Hakim Mohandas Amani
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Evaluation of usage patterns for web-based educational systems using web mining [PDF]
, 2001 Virtual courses often separate teacher and student physically from one another, resulting in less direct feedback. The evaluation of virtual courses and other computer-supported educational systems is therefore of major importance in order to monitor ...
Donnellan, David, Pahl, Claus
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