Results 61 to 70 of about 8,705,370 (258)

New technologies, new pedagogies: Mobile technologies and new ways of teaching and learning [PDF]

open access: yes, 2008
This paper describes a major development and research study that investigated the use of mobile technologies in higher education. The project investigated the educational potential of two ubiquitous mobile devices: Palm smart phones and iPod digital ...
Brian Ferry   +9 more
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Modern aspects of the use of foggy technologies in the educational process of higher educational institutions

open access: yes, 2020
Prokopenko A. Modern aspects of the use of foggy technologies in the educational process of higher educational institutions / A. Prokopenko // Освітні Обрії / Івано-Франків. обл. ін-т післядиплом. освіти пед. працівників. – 2020. – Вип. 1(50). – С.
Prokopenko, Аlena
core  

iPods in early childhood: Mobile technologies and story telling [PDF]

open access: yes, 2008
Mobile technologies are making inroads in many aspects of education. The potential of many of these devices is being explored in a range of educational environments but early childhood educators are not commonly early adopters of these new technologies ...
Verenikina, I.   +2 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

MODERN ONLINE EDUCATIONAL TECHNOLOGIES [PDF]

open access: yes, 2020
This article discusses the principles of modern online educational technologies, as well as various classifications of online educational resourcesВ данной статье рассматриваются принципы современных образовательных онлайн-технологий, а также приводятся ...
Yarina, S. Y., Ярина, С. Ю.
core   +1 more source

The Emergence of Educational Technology [PDF]

open access: yes, 2008
This paper traces the emergence of Information Technology (IT) for educational purposes. It begins with a discourse on the relationship between culture and educational technology. A key premise is that culture is an important influence in education. Similarly, the evolution of educational technology is very much intertwined with culture.
Elizabeth Koh 0001, John Lim
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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