Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Empirical modelling principles to support learning in a cultural context [PDF]
Much research on pedagogy stresses the need for a broad perspective on learning. Such a perspective might take account (for instance) of the experience that informs knowledge and understanding [Tur91], the situation in which the learning activity takes ...
Beynon, Meurig, Roe, Chris P.
core
The Academic Library in the Information Age: Changing Roles [PDF]
This booklet addresses three important areas. First, expectations for the academic library in today's information age. It seemed critical to examine requirements for the library itself, before exploring what would be needed from its staff.
Consortium for Educational Technology for University Systems +1 more
core +2 more sources
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Implementation of digital and cloud technologies in the educational process of a university [PDF]
Juliya V. Makarenko +2 more
openalex +1 more source
Educational process modelling with workflow and time Petri nets : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Computer Science at Massey University, Palmerston North, New Zealand [PDF]
The research presented in this thesis describes how to use workflow management technology to model educational processes with a time axis. As workflow management technology has been widely used in modelling business processes, it has the potential to ...
Ruan, Yuwen
core
Education, Entrepreneurship and Immigration: America's New Immigrant Entrepreneurs, Part II [PDF]
Analyzes the educational backgrounds and career trajectories of immigrant entrepreneurs, finding that advanced education in science, technology, engineering, and mathematics is correlated with high rates of entrepreneurship and ...
AnnaLee Saxenian +3 more
core +1 more source
The purpose of this study was to investigate the associations between alternative certification preservice teachers’ levels of depression, stress, educational technology anxiety, self-efficacy for educational technology, and attitude towards using ...
Oğuzhan Atabek
semanticscholar +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Educational technology and the traditional lecture
I was recently invited to give a lecture at the opening of a new high-technology lecture theatre at Leeds Metropolitan University. It is one of the best examples of its kind I have seen.
Gabriel Jacobs
doaj +1 more source

