Results 141 to 150 of about 1,835,889 (325)

Suspended Tissue Open Microfluidic Patterning (STOMP)

open access: yesAdvanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack   +22 more
wiley   +1 more source

EE-2 Core

open access: yes, 1982
This is a report concerning the petrography of core from EE-2. Special emphasis has been placed on fractures. Unfortunately, there is no orientation data available for these cores.
openaire   +3 more sources

Responsive ROS‐Augmented Prodrug Hybridization Nanoassemblies for Multidimensionally Synergitic Treatment of Hepatocellular Carcinoma in Cascade Assaults

open access: yesAdvanced Science, EarlyView.
This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng   +16 more
wiley   +1 more source

Motivational processes in physical education and objectively measured physical activity among adolescents

open access: yesJournal of Sport and Health Science, 2020
Purpose: Grounded in self-determination theory (SDT), the present study tested how students’ perceptions of autonomy support from physical education teachers predicts objectively measured moderate-to-vigorous physical activity (MVPA) of adolescents ...
Hanna Kalajas-Tilga   +4 more
doaj  

Nanogenerator Neuromodulation to Enable Locomotion Rehabilitation for Spinal Cord Injury via Epidural Electrical Stimulation

open access: yesAdvanced Science, EarlyView.
A hybrid nanogenerator (H‐NG) has been developed to be applied in epidural electrical stimulation (EES). Compared with a commercial stimulus generator (SG), the H‐NG can elicit hindlimb locomotion in rats with much lower electrical parameters and much smaller individual differences.
Cong Li   +12 more
wiley   +1 more source

Comprehensive Study of Li Deposition and Solid Electrolyte Cracking by Integrating Simulation and Experimental Data

open access: yesAdvanced Science, EarlyView.
This study presents a phase‐field model integrating mechanical constraints, solid–solid contact, and large‐strain mechanochemical coupling to characterize lithium deposition and electrolyte cracking. Results show that reducing mechanical constraints, with good electrode–electrolyte contact, suppresses dendrite eruption in cracks and extends battery ...
Chen Lin, Haihui Ruan, Ming‐Sheng Wang
wiley   +1 more source

EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation

open access: yesAdvanced Science, EarlyView.
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi   +12 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

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