Results 241 to 250 of about 2,101,185 (345)

Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance

open access: yesAdvanced Science, EarlyView.
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang   +13 more
wiley   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

open access: yesAdvanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma   +10 more
wiley   +1 more source

Probing the Higgs Portal to a Strongly-Interacting Dark Sector at the FCC-ee [PDF]

open access: green
Cesare Cazzaniga   +5 more
openalex   +1 more source

Lewis Acid‐Activated Charge Trapping in Dielectric Polymers for Superior High‐Temperature Electrostatic Energy Storage

open access: yesAdvanced Science, EarlyView.
Lewis acid–base molecular engineering tailors the lowest unoccupied molecular orbital of polymers to form deep, homogeneous charge traps in commercial polyetherimide (PEI). These deep traps effectively inhibit the transport of injected charge carriers from electrodes, ultimately enabling ultrahigh energy density and thermal stability in dielectric ...
Lu Fan   +21 more
wiley   +1 more source

Digital Pathology with AI for Cervical Biopsies: Diagnostic Accuracy at the CIN2+ Threshold. [PDF]

open access: yesCancers (Basel)
Andreassen AK   +4 more
europepmc   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang   +6 more
wiley   +1 more source

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