Results 241 to 250 of about 1,835,889 (325)

Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gorlin‐Goltz Syndrome (GGS) is a rare autosomal dominant genetic disorder encompassing a diverse range of clinical manifestations, including congenital anomalies and predisposition to cancer. Pathogenic variants in PTCH1 and SUFU account for up to 79% and 6% of cases, respectively. Currently, an estimated 15%–27% of individuals with a clinical
V. Taliercio   +13 more
wiley   +1 more source

Expressed Emotions in Families of Patients With Bipolar Disorder. [PDF]

open access: yesCureus
Verma M   +5 more
europepmc   +1 more source

Synthesis of a BINOL‐Derived Sulfide Catalyst Bearing a Diphenylmethanol Unit and Its Application in Asymmetric Bromolactonizations

open access: yesAsian Journal of Organic Chemistry, EarlyView.
The excellent catalytic performance of a BINOL‐derived sulfide catalyst bearing a diphenylmethanol unit was demonstrated in the highly enantioselective synthesis of γ‐butyrolactones via bromolactonization. Abstract A BINOL‐derived sulfide catalyst bearing a diphenylmethanol unit was prepared.
Yasuaki Furuya   +2 more
wiley   +1 more source

Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis

open access: yesAsian Journal of Organic Chemistry, EarlyView.
This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley   +1 more source

C3‐Symmetric Chiral Cage‐Shaped Phosphates: Synthesis and Application as Organocatalysts in Asymmetric Iodolactonizations

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Two C3‐symmetric cage‐shaped phosphates were successfully synthesized and their activity as chiral Lewis‐basic catalysts for enantioselective iodocyclizations was evaluated. The different tethered groups of these phosphates influences their catalytic performance, leading to substrate‐dependent variations in reactivity and selectivity, showcasing the ...
Xiao Liu, Akihito Konishi, Makoto Yasuda
wiley   +1 more source

Home - About - Disclaimer - Privacy