Results 281 to 290 of about 2,013,374 (364)

HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer   +52 more
wiley   +1 more source

Stability and Release Characteristics of Core‐Shell Beads with Emulsion Core Under Gastrointestinal Conditions

open access: yesAdvanced NanoBiomed Research, EarlyView.
A combined emulsion–core‐shell structure system is developed for targeted delivery of lipophilic compounds to the proximal intestine. Using vitamin D3‐loaded sunflower oil emulsions, the core‐shell structure enhances droplet stability, encapsulation efficiency, and gastric protection.
Fariba Malekpour Galogahi   +3 more
wiley   +1 more source

Precision Photochemistry: Every Photon Counts

open access: yesAngewandte Chemie, EarlyView.
Every photon used in a photochemical reaction has the power to dictate the outcome of the reaction. We present a framework whereby understanding the role that each photon has in a reaction can enablechemists to realise the true power of photochemistry and dramatically improve reaction outcomes.We coin this field Precision Photochemistry.
Fred Pashley‐Johnson   +11 more
wiley   +1 more source

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review. [PDF]

open access: yesFront Cell Neurosci
Silva CBG   +12 more
europepmc   +1 more source

Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions

open access: yesAngewandte Chemie, EarlyView.
In this study, we capitalize on the versatility offered by genetic code expansion to develop a proficient photoenzyme for [2 + 2]‐cycloadditions that is enantiocomplementary to our recently developed photoenzyme EnT1.3. By repositioning the genetically programmed benzophenone photosensitizer and subsequent directed evolution, we have developed an ...
Chuanjie Sun   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy