Results 291 to 300 of about 2,013,374 (364)

Aspen-EE: An Agent-Based Model of Infrastructure Interdependency

open access: green, 2000
David Barton   +4 more
openalex   +2 more sources

Regioselective Hydration of Terpenes with Cofactor‐Independent Carotenoid 1,2‐Hydratase

open access: yesAngewandte Chemie, EarlyView.
This study reveals a highly regioselective and cofactor‐independent enzymatic approach to terpene and terpenoid hydration using a carotenoid 1,2‐hydratase from Rubrivivax gelatinosus. Beyond detailing reaction optimization strategies, an extensive substrate scope, and scale‐up potential, it explores mutagenesis and structural modeling to identify key ...
Philip Horz   +6 more
wiley   +1 more source

Totalsynthese und Strukturkorrektur von (−)‐Sodagnitin E

open access: yesAngewandte Chemie, EarlyView.
Das Malabarican‐Triterpen Sodagnitin E ist ein in verschiedenen Pilzen vorkommendes Chromogen. Die vorliegende Arbeit stellt sowohl die erste Totalsynthese von (−)‐Sodagnitin E als auch die erste Synthese eines Malabaricans überhaupt dar. Die konvergente Synthese basiert auf der Verknüpfung zweier enantioselektiv hergestellter Fragmente mittels ...
Philipp Schoch, Tanja Gaich
wiley   +1 more source

On‐Surface Synthesis and Characterization of Cumulene‐Linked Stone‐Wales Polymers

open access: yesAngewandte Chemie, EarlyView.
On‐surface synthesis of one‐dimensional polymers featuring Stone‐Wales defects and cumulene linkages is demonstrated via thermally and light‐induced reactions on Au(111). STM, nc‐AFM, and Raman spectroscopy, complemented by theory calculations, reveal their chemical structure with a non‐planar geometry, and a distinct electronic bandgap of 1.8 eV ...
Elena Pérez‐Elvira   +15 more
wiley   +1 more source

Engineered C–N Lyases for Stereoselective Synthesis of Tertiary Amines

open access: yesAngewandte Chemie, EarlyView.
EDDS lyase was subjected to iterative cycles of site‐saturation mutagenesis and screened for increased activity for the addition of 2‐((methylamino)methyl)aniline to fumarate. The final mutant, EDDS lyase CEA, accepts various N‐methyl‐1‐phenylmethanamines derivatives, yielding N,N‐disubstituted L‐aspartic acids, as well as several ortho‐substituted ...
Laura Bothof   +4 more
wiley   +1 more source

Steuerbare endo/exo‐Selektivität in direkten katalytisch‐ asymmetrischen 1,3‐dipolaren Cycloadditionen mit polyfunktionellen Lewis‐Säure‐/Azolium‐Aryloxid‐Katalysatoren

open access: yesAngewandte Chemie, EarlyView.
Ein neuartiges Konzept für katalytische asymmetrische 1,3‐dipolare Cycloadditionen mit Iminoestern verwendet modulare polyfunktionelle Lewis‐Säure‐/Azolium‐Aryloxid‐Betain‐Katalysatoren, die die endo‐ und exo‐Selektivität durch Anpassungen des Metallzentrums, des Azoliums und der Sterik steuern. DFT‐Studien zeigen eine nahezu perfekte räumliche Passung
Adrian Bürstner   +13 more
wiley   +1 more source

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