Commentary: The ETP-based APC resistance assay remains the gold standard for evaluating the APC resistance phenotype in users of combined oral contraceptives. [PDF]
Morimont L, Douxfils J.
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Chirality Makes or Breaks Chemically Driven Self‐Assembly
Chirality‐controlled reaction cycles: Reaction cycles are constructed to respond to the chirality (handedness) of an acylating agent. Left‐ and right‐handed aminoacyl phosphate esters modulate the structure, lifetime, and transformation of transient (thio)ester intermediates, enabling control over distinct chemical pathways using molecules that are ...
Lenard Saile+5 more
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Early versus delayed postoperative extubation after elective neurosurgical treatment of brain metastasis. [PDF]
Khalafov L+14 more
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Total Synthesis of Feglymycin Using Umpolung Amide Synthesis
A total synthesis of the antiviral feglymycin is described, leveraging enantioselective umpolung amide synthesis (UmAS). The strategic use of UmAS to prepare the aryl glycine‐rich tridecapeptide reduced hazardous amide coupling agents by 50%, and replaced asymmetric synthesis reliant on toxic transition metals by organocatalysis.
Preston C. Gourville+10 more
wiley +1 more source
Evidence on the Porter hypothesis: China's Resource Tax Law may be a path to achieve corporate sustainable development. [PDF]
Zhang X, He Y.
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We present an asymmetric formal synthesis of pseudolaric acid B, for which we developed a new family of substrates with an epoxide geminally tethered to a sidechain bearing a furan, which undergoes a TESOTf‐catalyzed intramolecular (4+3) cycloaddition to yield the trans‐fused perhydroazulene core and the requisite quaternary stereocenter of the natural
Zengsheng Yin+7 more
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The Ascent of Supramolecular Polymers and Gels in Asymmetric Catalysis. [PDF]
Chen R, Bouteiller L, Raynal M.
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Chiral Induction and Memory via Supramolecular Deracemization
The helical chirality of a dynamic crown‐ether switch can, by light‐ or redox‐switching to a prochiral state, be erased and subsequently stereoselectively re‐formed by relaxation in the presence of a point‐chiral ammonium guest. This unique supramolecular deracemization enables facile transfer and stable memory of chiral information. Abstract Chirality
Robert Hein+3 more
wiley +1 more source
Combined enriched environment and fluoxetine enhance myelin protein expression in the prefrontal cortex of a chronic unpredictable stress depression model. [PDF]
Gu J+10 more
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