ESR1 overexpression is a biomarker of relapse and worse prognosis in stage I endometrioid endometrial carcinoma [PDF]
Brazilian Journal of Medical and Biological ResearchEndometrial cancer (EC) is the most common pelvic gynecologic malignancy in developed countries, and its incidence is also increasing in developing countries. Endometrioid endometrial carcinoma (EEC) is the most frequent subtype.
C.B.P. Chaves +9 more
doaj +1 more source
European central bank independence and inflation persistence [PDF]
Central Banks;EEC;monetary ...
Schaling, E.
core +1 more source
A Turning Point: past and future of the European Community's relations with Eastern Europe. Biblio-Flash No 24, 1989 [PDF]
, 1989 The signature on 25 June 1988 in Luxembourg of the EEC-CMEA (1) Joint Declaration, of which a text is annexed to this article, marked the establishment of official relations between the European Community and the CMEA and at the same time gave the ...
Maslen, John
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Gynecology and Obstetrics Clinical MedicineEndometrial carcinoma (EC) is one of the most common malignancies of the female reproductive system, with an increasing incidence and mortality rate. Endometrioid EC (EEC) was the most common type of EC.
Xiaobo Zhang, Yixuan Zhen
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The Reciprocity Requirement of the Second Banking Directive of the European Economic Community [PDF]
, 1988 This article discusses the revised Article 7(4) of the European Communities\u27 Proposal for a Second Council Directive on the Coordination of Laws, Regulations and Administrative Provisions Relating to the Taking-up and Pursuit of the Business of Credit
Gruson, Michael, Nikowitz, Werner
core +1 more source
Survey on Data-Centric based Routing Protocols for Wireless Sensor Networks
, 2017 The great concern for energy that grew with the technological advances in the field of networks and especially in sensor network has triggered various approaches and protocols that relate to sensor networks. In this context, the routing protocols were of
Rasbi, Khalid Al +2 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source