Results 91 to 100 of about 616,724 (329)
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei+4 more
wiley +1 more source
Navigating the multifaceted landscape of culture and social work
Faced with increased global migration, there is a growing concern that social workers need more training in- and knowledge of culture and ethnicity.
Maria Gussgard Volckmar-Eeg+1 more
doaj +1 more source
This study examines how the human hippocampus encodes visual memory categories. By decoding spiking activity from CA3 and CA1 neurons using an interpretable model, it reveals that category‐specific representations emerge from distributed temporal coding.
Xiwei She+17 more
wiley +1 more source
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan+16 more
wiley +1 more source
This study shows that enhanced brain‐to‐heart coupling is a precursor of anxiety reduction following a virtual reality‐based non‐pharmacological intervention. Driven by midline beta rhythms, this effect suggests the involvement of central‐autonomic interactions.
Idil Sezer+6 more
wiley +1 more source
AADNet: An End-to-End Deep Learning Model for Auditory Attention Decoding
Auditory attention decoding (AAD) is the process of identifying the attended speech in a multi-talker environment using brain signals, typically recorded through electroencephalography (EEG). Over the past decade, AAD has undergone continuous development,
Nhan Duc Thanh Nguyen+4 more
doaj +1 more source
Neutron Electric Dipole Moment from colored scalars⋆
We present new contributions to the neutron electric dipole moment induced by a color octet, weak doublet scalar, accommodated within a modified Minimal Flavor Violating framework.
Fajfer Svjetlana, Eeg Jan O.
doaj +1 more source
A wireless soft athlete bioelectronic system offers a real‐time continuous monitoring of various physiological signals and metabolites during exercise. Abstract Wearable devices have become essential tools for monitoring athletes' health and performance.
Tae Woog Kang+12 more
wiley +1 more source
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou+15 more
wiley +1 more source