Results 161 to 170 of about 376,252 (303)

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

Annals of Neurology, EarlyView.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau, Sebastien Arthaud, Leila Langbour, Silvia Melzi, Aurelie Richard‐Mornas, Hannah Doudoux, Benjamin Rolland, Laure Peter‐Derex, Christelle Peyron   +8 more
wiley   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Hippocampal Seizure‐Related Burden is Associated with Accelerated Long‐Term Forgetting in Focal Epilepsy

Annals of Neurology, EarlyView.
Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu, Isabelle Lambert, Olivier Felician, Samuel Medina Villalon, Agnès Trébuchon, Fabrice Bartolomei   +5 more
wiley   +1 more source

Tilia Tomentosa promotes sleep, preserving sleep structure. [PDF]

NPJ Biol Timing Sleep
Di Soccio A, Canova M, Rizzo N, Lodovichi C.   +3 more
europepmc   +1 more source

Application of signal processing to respiratory cycle related EEG change (RCREC) in children

, 2014
Sleep is an important part of everyday life. It directly affects daytime cognition and general performance. In children, sleep is a crucial requirement for growth and learning and lack of sleep may manifest itself as a long lasting developmental deficit.
Motamedi Fakhr, Shayan
core  

Evaluation of MPEG-4 AAC Audio Codec Using EEG and EMG Signals for Use with DICOM® Neurophysiology. [PDF]

J Med Syst
Galanti M, Battaglia F, Gugliandolo G, Omland PM, Nilsen KB, Breevoort S, Herring MN, Kurent J, Chen IA, Vu T, Wuthrich K, Donato N, Gebregziabher M, Campobello G, Dean BC, Halford JJ.   +15 more
europepmc   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, EarlyView.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source

Wireless Electroencephalography in Research on Children With Developmental Disabilities: Scoping Review. [PDF]

J Med Internet Res
Park N, Shin Y, Kang J, Lee YE, Lee A.
europepmc   +1 more source

The pelvis doesn't walk by itself: Wider pelves reduce the cost of walking over unstable surfaces

The Anatomical Record, EarlyView.
Abstract Walking over variable and/or unstable terrain is a key aspect of daily life and was crucial to the evolution of bipedalism. The ability to find gait solutions that maintained stability over uneven terrain for the least increase in metabolic cost was likely a hallmark of locomotor effectiveness in early humans, in particular acting as an ...
Cara Wall‐Scheffler, Taylor Morscheck, Katelyn McCollor   +2 more
wiley   +1 more source