Results 41 to 50 of about 191,604 (267)
Epilepsia OpenObjective To investigate the excitatory–inhibitory imbalance in drug‐resistant Juvenile Myoclonic Epilepsy (DR‐JME) patients using event‐related potentials during motor and cognitive tasks.
Leviashvilli Sarah +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Archives of Disease in Childhood, 1999 Editor,—We welcome the debate on the timing of EEG examinations.1 The practice of delaying the EEG until after a second seizure began when epilepsy syndromes were unrecognised. The EEG was then of little help in predicting prognosis or guiding treatment, but has been transformed by the recognition of epilepsy syndromes. Although some of these syndromes
openaire +2 more sources
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Seizure, 2017 Highlights: * Here we report on accidental oxcarbazepine intoxication in a single patient. * In this patient we demonstrate EEG-documented acute downbeat nystagmus (DBN). * Such DBN most likely reflects acute oxcarbazepine-induced cerebellar-dysfunction. * New-onset DBN on EEG should prompt checking for antiepileptic drug-intoxication.
Tarnutzer, A A, Imbach, L L
openaire +3 more sources
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Forventninger og helserett ved Ila fengsel og forvaringsanstalt
Kritisk Juss, 2023 Soningsforholdene ved Ila fengsel og forvaringsanstalt har vært kritisert gjennom flere år, særlig med henblikk på isolasjon. Forventningene om forbedring er delvis utformet som forventninger til helsevesenet.
Øyvind Holst, Hanne Eeg-Henriksen
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source