Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Management of endotracheal tube dislodgement during transoral oropharyngolaryngeal surgery: a multicenter cross-sectional survey study. [PDF]
Li F, Huang D, Liang Z.
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Carbon emission governance and public health efficiency in transitional China: Regional differences and spatial aggregation. [PDF]
Wei Y, Guo L, Tao Q, Wei H.
europepmc +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Impact Assessment of Spatial Mismatch Between Grain Production and Consumption on Non-Point Source Pollution and Carbon Emissions from Grain Production in China. [PDF]
Yang H, Sieber S.
europepmc +1 more source
The Influence of Match-up Degree and Brand Image on Advertising Effect
Now, combination of advertising and product spokesperson is almost a standard procedure of advertising design. However, in a variety of product endorsement ads by using the good looking spokesperson to speak, is already very common phenomenon.
Li, Chi-Yang
core
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The effect of different osseodensification techniques on implant stability in the maxillary anterior esthetic zone. A split-mouth randomized clinical trial. [PDF]
Ali MA, ElSabbagh AM, El-Mahallawy Y.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

