Results 81 to 90 of about 12,083,096 (149)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Confounding and effect modification: their significance in medical research
, 1997 Confounding and effect modification, two very important statistical concepts that may occur both in the statistical modelling of epidemiological data and other medically related data are seldom considered during the analysis of data.
B.A. Olayinka (19312069)
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Combining play therapy with behavior modification in child counseling [PDF]
, 2004 Plan BThe purpose of this study was to identify how child therapists perceive and utilize both behavior modification and play therapy. Sixty surveys were sent to child therapists in Wisconsin.
Lisec, Sara J.
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Lifestyle modification and hypertension prevention [PDF]
BACKGROUND: Hypertension, a clear risk factor for cardiovascular diseases, affects nearly one billion people worldwide. Recent statistics have reported increasing mortality due to hypertension which reveals the importance of prophylactic strategies in ...
قربانی, اعظم +1 more
core
Four types of effect modification -- a classification based on directed acyclic graphs
, 2008 By expressing the conditional causal risk difference as a sum of products of stratum specific risk differences and conditional probabilities, it is possible to give a classification of the types of causal relationships that can give rise to effect ...
Tyler J. Vanderweele, James M. Robins
core
Association of psychological symptoms with poor sleep quality in adults: a cross-sectional network analysis and effect modification by thyroid hormones. [PDF]
Front Endocrinol (Lausanne)Xie M +7 more
europepmc +1 more source