Results 131 to 140 of about 5,753,189 (269)

Treatment of posttraumatic stress disorder (PTSD). [PDF]

Dialogues Clin Neurosci
Bandelow B.
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Altered Effective Connectivity Within the Frontoparietal Network in Alzheimer's Disease and Its Modulation by Acupuncture: A Resting-State <i>f</i>MRI Study. [PDF]

Neuropsychiatr Dis Treat
Wei YT, Li L, Xie WT, Wang Y, Zhao YR, Zhang RZ, Ma L, Yan XK.   +7 more
europepmc   +1 more source

Ceiling Effect Is Not the Only Effect [PDF]

Annals of Emergency Medicine, 2018
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Perinatal interventions for parents with exposure to adverse childhood experiences: A narrative review of suitability for implementation in primary care. [PDF]

Infant Ment Health J
Chen JJ, Magnuson K, Edgar VB, Stewart SM.   +3 more
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Thermally modulated resonant quantum transport in asymmetric nanoscale junctions for optimal bias and power generation analysis. [PDF]

Sci Rep
Aly AH.
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

A feasibility study on inferring connectivity changes in frontal lobes of MDD patients via spectral DCM. [PDF]

Brain Inform
Wang X, Li S, Zhang M, Yang C.
europepmc   +1 more source