Results 91 to 100 of about 1,616,662 (316)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
"Measuring Capacity Utilization in OECD Countries: A Cointegration Method" [PDF]
This paper derives measures of potential output and capacity utilization for a number of OECD countries, using a method based on the cointegration relation between output and the capital stock.
Jamee K. Moudud, Anwar M. Shaikh
core
Nurturing Capacity in Developing Countries : From Consensus to Practice
, 2003 There is an emerging consensus that capacity building in developing countries must shift from supply-side, donor-driven to demand-led approaches. Three areas in which this is critical are evaluation capacity, the
Nair, Govindan G.
core +1 more source
Effective Energy Efficiency under Delay–Outage Probability Constraints and
SensorsThe paradigm of the Next Generation cellular network (6G) and beyond is machine-type communications (MTCs), where numerous Internet of Things (IoT) devices operate autonomously without human intervention over wireless channels.
Fahad Qasmi +3 more
doaj +1 more source
Effect of Conclevan on Endurance Capacity in Mice
Biological and Pharmaceutical Bulletin, 2012 The purpose of this study was to clarify the anti-fatigue effect of Conclevan, which is mainly composed of liver hydrolysate, via a forced swimming test using mice. Conclevan was administered to mice for 6 weeks, and a forced swimming test was conducted to measure swimming time.
Ikarashi, Nobutomo +6 more
openaire +3 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Aid effectiveness and capacity development: Implications for economic growth in developing countries [PDF]
"Although adequate country capacity is considered to be one of the critical missing factors in development outcomes, a lack of understanding of how capacity contributes to economic development and of how to account for the contribution of capacity ...
Sanyal, Prabuddha, Babu, Suresh
core
AlgorithmsWe introduce Self-Competitive Distillation (SCD), a parameter-neutral training strategy aimed at influencing optimization dynamics without increasing model size or relying on external teachers.
Weidong Zhang +4 more
doaj +1 more source
The effects of mergers with dynamic capacity accumulation [PDF]
International Journal of Industrial Organization, 2009 Abstract The U.S. antitrust law enforcement agencies often base their assessment of mergers on a model with asymmetric costs. However, in many near-homogeneous product industries there is evidence that cost differences are minor and capacity differences seem a more reasonable explanation of firm heterogeneity.
openaire +1 more source