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Dynamic causal modeling (DCM) is a method for analyzing functional magnetic resonance imaging (fMRI) and other functional neuroimaging data that provides information about directionality of connectivity between brain regions.
Andrew D. Snyder +11 more
doaj +1 more source
Major depressive disorder (MDD) is a severe mental disorder and is lacking in biomarkers for clinical diagnosis. Previous studies have demonstrated that functional abnormalities of the unifying triple networks are the underlying basis of the ...
Yanling Li +5 more
doaj +1 more source
Sparse Estimation of Resting-State Effective Connectivity From fMRI Cross-Spectra
In functional magnetic resonance imaging (fMRI), functional connectivity is conventionally characterized by correlations between fMRI time series, which are intrinsically undirected measures of connectivity. Yet, some information about the directionality
Carolin Lennartz +9 more
doaj +1 more source
Mechanisms of cognitive-behavioral therapy for obsessive-compulsive disorder involve robust and extensive increases in brain network connectivity. [PDF]
Cognitive-behavioral therapy (CBT) is effective for obsessive compulsive disorder (OCD); however, little is understood about its mechanisms related to brain network connectivity.
Cheng, G +7 more
core +1 more source
ObjectivesThe network mechanism underlying the initial response to antiseizure medication in epilepsy has not been revealed yet. Given the central role of the thalamus in the brain network, we conducted a case-control study to investigate the association
Jiyuan Zhong +4 more
doaj +1 more source
Exercise Training and Functional Connectivity Changes in Mild Cognitive Empairment and Healthy Elders [PDF]
Background: Effective interventions are needed to improve brain function in mild cognitive impairment (MCI), an early stage of Alzheimer’s disease (AD).
Alfini, Alfonso J. +5 more
core +2 more sources
Reorganization of brain networks in aging: A review of functional connectivity studies.
Healthy aging (HA) is associated with certain declines in cognitive functions, even in individuals that are free of any process of degenerative illness.
Roser eSala-Llonch +2 more
doaj +1 more source
Mild cognitive impairment (MCI) is generally considered to be a key indicator for predicting the early progression of Alzheimer’s disease (AD). Currently, the brain connection (BC) estimated by fMRI data has been validated to be an effective diagnostic ...
Weikai Li +8 more
doaj +1 more source
Altered structural and effective connectivity in anorexia and bulimia nervosa in circuits that regulate energy and reward homeostasis. [PDF]
Anorexia and bulimia nervosa are severe eating disorders that share many behaviors. Structural and functional brain circuits could provide biological links that those disorders have in common.
Frank, GKW +3 more
core +1 more source
A tutorial on group effective connectivity analysis, part 2: second level analysis with PEB [PDF]
This tutorial provides a worked example of using Dynamic Causal Modelling (DCM) and Parametric Empirical Bayes (PEB) to characterise inter-subject variability in neural circuitry (effective connectivity).
Cagnan, Hayriye +6 more
core +2 more sources

