Results 31 to 40 of about 181,649 (260)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

EFFECTIVE CONTRACT SYSTEM FOR UNIVERSITY RESEARCH AND TEACHING STAFF

open access: yesВысшее образование в России, 2016
The article reports on experience of the effective contract system implementation for research and teaching staff at National Research Tomsk Polytechnic University.
Petr S. Chubik   +5 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

An effective system of material incentives for pedagogical workers of professional education

open access: yesПутеводитель предпринимателя, 2020
The article describes the main problems in the system of stimulation of work of pedagogical workers of University, as well as secondary and primary professional education, the necessity of creation of effective system of stimulation and motivation of ...
E. I. Velmisova
doaj  

Criteria for Qualification of the Contract Based on Analysis of the agreement of Contracting Parties in Iranian Law, Ja'fari jurisprudence and French law [PDF]

open access: yesپژوهشنامه حقوق تطبیقی
The most important issue in the distinction between validity and invalidity, as well as the conditions, rules, and effects of a contract, is determining the nature of the contract or, in other words, describing the contract.
Mohammad Mansouri   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

WHETHER THERE WILL BE AN EFFECT FROM EFFECTIVE CONTRACT IN THE SYSTEM OF HIGHER EDUCATION?

open access: yesВысшее образование в России, 2017
The article addresses the issues concerning the implementing of effective contract in higher education institutions. The author analyzes this problem through a prism of possible increase of labor productivity of university teaching staff and adduces ...
G. N. KRAYNOV
doaj  

The principles of the formation of personnel academic strategies in Belarus

open access: yesEkonomika Nauki, 2019
The article presents the results of a scientific study of the current state of the motivational component of academic workers in the Republic of Belarus. The trends of academic behavior of the faculty of Belarusian universities are determined.
N. V. Makovskaya
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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