Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy. [PDF]
Lin Y +8 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
The objective of this experiment was to evaluate the effect of utilization of soybean meal or corn gluten meal on in situ ruminal degradabilities of diets, based on coastcross hay, corn and one of the nitrogen sources, fed to bulls, with average weight ...
Malheiros, Euclides Braga [UNESP] +3 more
core
Tuning scaffold degradation with non-natural peptidomimetics to control human umbilical vein endothelial cell morphology and vessel formation. [PDF]
Halwachs KN +4 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Ultralow concentrations of curcumin as a structural modifier in chitosan coatings for eco-friendly postharvest preservation of strawberries. [PDF]
Silva HS +3 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
The experiment aimed to explore the effects of two types of Lentinus edodes on the nutritional characteristics and ruminal degradability of wheat straw. Two strains of Lentinus edodes (X3 and 243) were selected to ferment wheat straw in solid state, with
GAO Xu-hong, LIANG Xiao-jun, MAO Lei
doaj
Ruminal and Postruminal Digestibility Parameters of Locally Produced Non-GMO Full-Fat Soybeans, Extruded Full-Fat Soybeans and Soybean Cake in Cattle. [PDF]
Śliwiński B, Witaszek K, Kostecki J.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source

