Results 51 to 60 of about 5,460,297 (306)

Multitrophic diversity effects of network degradation [PDF]

Ecology and Evolution, 2016
AbstractPredicting the functional consequences of biodiversity loss in realistic, multitrophic communities remains a challenge. No existing biodiversity–ecosystem function study to date has simultaneously incorporated information on species traits, network topology, and extinction across multiple trophic levels, while all three factors are ...
Nichols, Elizabeth, Peres, C. A., Hawes, J. E., Naeem, S.   +3 more
openaire   +5 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Controlling the degradation of a protection effect

Computational and Applied Mathematics
We study the optimal placement of limited intervention zones that reduce the degradation of a protection effect in a crop field. To this end, we formulate an optimal control problem for a protection model described by a parabolic equation. The control represents the intervention zones, and the objective is to maximize the protection over the field ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Ruminal Degradability Of Agro-industrial Fruit Residues [PDF]

, 2017
The aim of this study was to evaluate the chemical composition and ruminal degradability of the dry matter (DM), crude protein (CP) and neutral detergent fiber (NDF) of fruit residues. Three fistulated sheep were held collectively in a pen, and fed daily
Da Silva Maia I.S.A., Da Silva Lagos Cortes Assis L.C., Braga A.P., De Souza Gonçalves J., De Souza C.M.S., De Andrade Ferreira Amâncio A.V., Gerra D.G.F.   +6 more
core   +1 more source

In Vitro and In Situ Evaluation of Fermented High Moisture Corn and Ear Corn as Alternative Feedstuffs for Feedlot Calves

Tropical Animal Science Journal
High-moisture corn products offer potential advantages in intensive cattle feeding systems by providing high-energy feedstuffs while allowing earlier harvest.
H. Rajaei-Sharifabadi, D. Villalba, J. Mora, G. de la Fuente, J. Balcells, A. R. Seradj   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Caracterização, fracionamento protéico, degradabilidade ruminal e digestibilidade in vitro da matéria seca e proteína bruta do resíduo de cervejaria úmido e fermentado = Characterization, protein fractioning, dry matter and crude protein rumen degradability and in vitro digestibility of wet and fermented brewer’s grain

Acta Scientiarum: Animal Sciences, 2007
Foram avaliadas as frações da proteína e dos carboidratos, a degradabilidade ruminal efetiva (DE) da matéria seca (MS) e proteína bruta (PB), a digestibilidade ruminal in vitro (DRIV) da MS e PB, a digestibilidade intestinal in vitro (DIIV) da proteína ...
Luiz Juliano Valério Geron, Lúcia Maria Zeoula, Antônio Ferriani Branco, Jacco Arnoud Erke, Odimari Priscila Pires do Prado, Guido Jacobi   +5 more
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source