Results 91 to 100 of about 519,680 (305)

Enabling sustainable service delivery by means of effective demand management in a local municipality

, 2011
Gabriel Tsietsi Banda
openalex   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

An effective IoT-based demand response for energy-efficient smart homes

Energy Informatics
The proliferation of energy demand with population growth and associated costs necessitated the development of advanced demand response (DR) strategies in smart grid (SG) environments. This study proposes a novel IoT-enabled Energy Management Controller (
Habibu M. A, S. Sivakumar, G. R. Kanagachidambaresan, E. S. Mwanandiye   +3 more
doaj   +1 more source

Keynes versus the Post Keynesians on the Principle of Effective Demand

, 2004
Jochen Hartwig
openalex   +2 more sources

Demand response for residential building heating: Effective Monte Carlo Tree Search control based on physics-informed neural networks [PDF]

, 2023
Fabio Pavirani, Gargya Gokhale, Bert Claessens, Chris Develder   +3 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Demanda efetiva no longo prazo e no processo de acumulação: o debate sraffiano a partir do projeto de Garegnani (1962)

Economia e Sociedade
Resumo O artigo discute a evolução do projeto sraffiano, iniciado em 1962 por Garegnani, de desenvolver uma teoria da demanda efetiva de longo prazo. Tratamos tanto dos aspectos metodológicos quanto analíticos, começando com a questão da compatibilidade ...
Vivian Garrido Moreira, Franklin Serrano
doaj   +1 more source

Uncertainty Shocks in a Model of Effective Demand: Reply [PDF]

, 2018
Susanto Basu, Brent Bundick
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source