Results 61 to 70 of about 7,555,861 (292)

Estimation of Effective Diffusion Coefficient of O2 in Ash Layer in Underground Coal Gasification by Thermogravimetric Apparatus

Energies, 2018
Underground coal gasification (UCG) proceeds generally in the presence of an ash layer on coal (or char) surface. The ash layer increases the mass transfer resistance of O2 to the gasification surface, which may become the limiting step of whole process.
Xi Lin, Qingya Liu, Zhenyu Liu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Impact of Pore Geometry and Water Saturation on Gas Effective Diffusion Coefficient in Soil

Applied Sciences, 2018
Gas flow in soil plays a crucial role in terrestrial ecosystems, and numerical simulation of their movement needs to know their effective diffusion coefficients.
Wulong Hu, Yao Jiang, Daoyi Chen, Yongshui Lin, Qiang Han, Yifei Cui   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Regulation of nuclear NF-κB oscillation by a diffusion coefficient and its biological implications. [PDF]

PLoS ONE, 2014
The transcription factor NF-κB shuttles between the cytoplasm and the nucleus, and nuclear NF-κB is known to oscillate with a cycle of 1.5-2.5 h following the application of external stimuli.
Daisuke Ohshima, Kazuhisa Ichikawa
doaj   +1 more source

Correlation for the Effective Gas Diffusion Coefficient in Carbon Paper Diffusion Media

Energy & Fuels, 2009
The understanding of mass transport limitations in polymer electrolyte membrane (PEM) fuel cells is crucial in the research and progress of this technology. The structure of the components, specifically the as diffusion layer (GDL), of PEM fuel cells, is complex. Thus, for the purpose of simulating mass transport in the GDL, the effect of the structure
Zamel, Nada, Li, Xianguo, Shen, Jun
openaire   +3 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Time-dependent diffusion coefficient of proton in polymer electrolyte membrane [PDF]

, 2009
We investigated the time-dependent self-diffusion coefficients of water, D(T eff), in polymer electrolyte membranes at 278 K. TheD(T eff) was measured from T eff=0.7 to 100 ms by field gradient NMR techniques.
Ohkubo, Takahiro, Ohira, Akihiro, Kidena, Koh   +2 more
core   +1 more source

Pixel-based time–intensity curve analysis and apparent diffusion coefficient mapping of sinonasal organized hematomas [PDF]

, 2010
We present dynamic contrast-enhanced (DCE) and diffusion-weighted magnetic resonance imaging (MRI) features in three cases of sinonasal organized hematoma. The DCE MRI was evaluated by analyzing the time-intensity curve patterns on a pixel-by-pixel basis
Sasaki, Miho, Miho Sasaki, Nakamura, Takashi, Takashi Nakamura   +3 more
core   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source