99 A multi-dimensional approach towards implementing the effective use of remote electrocardiographic monitoring – evaluation of clinical correlation and patient experience [PDF]
Muhammad Asad +4 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Anomalous dimension of a general effective gauge theory. Part I. Bosonic sector
We classify the physical operators of the most general bosonic effective gauge theory up to dimension six using on-shell methods. Based on this classification, we compute the complete one-loop anomalous dimension employing both on-shell unitarity-based ...
Jason Aebischer +2 more
doaj +1 more source
2, 84, 30, 993, 560, 15456, 11962, 261485, . . .: higher dimension operators in the SM EFT
In a companion paper [1], we show that operator bases for general effective field theories are controlled by the conformal algebra. Equations of motion and integration by parts identities can be systematically treated by organizing operators into ...
Brian Henning +3 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Generalized N-Dimensional Effective Temperature for Cryogenic Systems in Accelerator Physics
Investigations into the properties of generalized effective temperature are conducted across arbitrary dimensions. Maxwell–Boltzmann distribution is displayed for one, two, and three dimensions, with effective temperatures expressed for each dimension ...
Heetae Kim, Chang-Soo Park
doaj +1 more source
Constraints on dark matter annihilation to fermions and a photon
We consider Majorana dark matter annihilation to fermion-anti-fermion pair and a photon in the effective field theory paradigm, by introducing dimension 6 and dimension 8 operators in the Lagrangian.
Debtosh Chowdhury +2 more
doaj +1 more source
Sustained attention required for effective dimension-based retro-cue benefit in visual working memory. [PDF]
Liu R +7 more
europepmc +1 more source

