Results 271 to 280 of about 12,005,894 (331)

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Successful antipsychotic dose tapering leading to better cognition in patients with remitted psychosis: Results of Guided Antipsychotic Reduction to Reach Minimum Effective Dose (GARMED) trial. [PDF]

Psychol Med
Liu CI, Liu CM, Hsieh MH, Lin YT, Chien YL, Hwang TJ, Yen K, Liu CC.   +7 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Determining the effective dose of esketamine combined with propofol for painless hysteroscopy: a prospective dose-finding study. [PDF]

Front Pharmacol
Sheng Z, Liu X, Lin K, Liu J, Mao J, Qian X.   +5 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Determination of the 90% Effective Dose of Remimazolam Continuous Infusion for Preventing Emergence Delirium in Pediatric Patients Undergoing Adenoidectomy or Adenotonsillectomy with Sevoflurane: A Biased Coin Up-and-Down Sequential Trial Design. [PDF]

Drug Des Devel Ther
Yang ZS, Li D, Jiang Y, Xiao F, Yan HY.
europepmc   +1 more source

The 90% effective dose of ciprofol and propofol with S-ketamine for painless abortion: a randomized, double-blind, sequential dose-finding trial. [PDF]

Ther Adv Drug Saf
Tao Q, Shi Q, Xu T, Ye S.
europepmc   +1 more source

A Commentary on "Effective Dose of Epidural Hydromorphone for Analgesia Following Caesarean Section in Using Modified Dixon Sequential Method" [Letter]. [PDF]

J Pain Res
Wu S, Zhao Y, Li J.
europepmc   +1 more source

Effective dose of ciprofol combined with low-dose sufentanil for sedation of gastroscopy: a dose-finding study using a biased coin design. [PDF]

BMC Anesthesiol
Hu B, Guan T, Yu C, Wang D, Wang Q, Wang H.   +5 more
europepmc   +1 more source

Effective Dose Reduction of Emamectin Benzoate Through Inhibition of <i>Bx-SDR3</i> in Pine Wood Nematode Management. [PDF]

Int J Mol Sci
Zhuang Y, Xia R, Yang F, Xu Z, Liang G, Zhang R, Bao Y, Wang F.   +7 more
europepmc   +1 more source