Results 161 to 170 of about 4,744,635 (350)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Cosmic Microwave Background from Effective Field Theory

open access: yesUniverse, 2019
In this work, we study the key role of generic Effective Field Theory (EFT) framework to quantify the correlation functions in a quasi de Sitter background for an arbitrary initial choice of the quantum vacuum state. We perform the computation in unitary
Sayantan Choudhury
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Many-body perturbation theory for strongly correlated effective Hamiltonians using effective field theory methods

open access: yesSciPost Physics
Introducing low-energy effective Hamiltonians is usual to grasp most correlations in quantum many-body problems. For instance, such effective Hamiltonians can be treated at the mean-field level to reproduce some physical properties of interest. Employing
Raphaël Photopoulos, Antoine Boulet
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

On the power counting in effective field theories

open access: yesPhysics Letters B, 2014
We discuss the systematics of power counting in general effective field theories, focussing on those that are nonrenormalizable at leading order. As an illuminating example we consider chiral perturbation theory gauged under the electromagnetic $U(1)$ symmetry. This theory describes the low-energy interactions of the octet of pseudo-Goldstone bosons in
Gerhard Buchalla   +2 more
openaire   +4 more sources

Regge behavior in effective field theory

open access: yes, 2014
We derive the Regge behavior for the forward scattering amplitude in scalar field theory using the method of regions. We find that the leading Regge behavior to all orders can be obtained.
Donoghue, John F.   +2 more
core   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

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