Results 61 to 70 of about 9,107 (261)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

The effectiveness of the constitutional complaint as a legal remedy against the violation of constitutional rights

Problems of Legality, 2019
Анализируются юридически значимые последствия рассмотрения конституционных жалоб Конституционным Судом Украины с точки зрения эффективности защиты конституционных прав физических и юридических лиц – субъектов права на конституционную жалобу в системно-функциональной связи с другими средствами правовой защиты.
openaire   +5 more sources

Public Hearings as a Political and Legal Instrument of the Direct Democracy and Social Resource of the Local Government Activity Legitimacy

Èkonomika, Pedagogika i Pravo, 2015
In the present article author considers theoretical legal questions of carrying out public hearings in municipalities, municipal acts and practice of carrying out public hearings are analyzed, problems of legal regulation of public hearings in ...
Natalia N. Kuleshona
doaj  

Effectiveness of Legal Remedies Available to the Victims of Medical Negligence

Medical negligence continues to be a significant issue within healthcare systems globally. Although legal options are available to seek compensation for victims, their actual effectiveness is debated due to various systemic, procedural, and institutional challenges.
Ushasi Mandal, Dr. Ramesh Kumar
openaire   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

The Development of Complaint and Public Interest Disclosure Regulation in Hungary

Journal on European History of Law, 2019
In this study, I aimed to provide a legal historical overview of the right to petition and the right to public interest disclosure in Hungary. My goals were to cover a large period of time and to offer sufficient detail.
István Ambrus
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

EXTRAORDINARY REMEDIES AND CONSTITUTIONAL COMPLAINT IN SERBIAN CIVIL PROCEDURE AS AN ADMISSIBILITY CONDITION FOR ECtHR APPLICATIONS

Anali Pravnog Fakulteta u Beogradu
This article examines the European Court of Human Rights’ (ECtHR) approach to the exhaustion of extraordinary legal remedies and constitutional complaints in civil cases against Serbia.
JELENA TODIĆ, HRISTINA TODOROVIĆ
doaj   +1 more source