Advancements in Renal Imaging: A Comprehensive Systematic Review of PET Probes for Enhanced GFR and Renal Perfusion Assessment. [PDF]
Abdulrahman M +11 more
europepmc +1 more source
Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang +7 more
wiley +1 more source
THE EFFECT OF EXERCISE ON RENAL PLASMA FLOW IN NORMAL MALE SUBJECTS [PDF]
C B, Chapman +4 more
openaire +2 more sources
Has the time come to change the treatment criteria for patients with chronic kidney disease? The "hypofiltering nephron" hypothesis. [PDF]
Romano G, Ferraccioli G, Colussi G.
europepmc +1 more source
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang +13 more
wiley +1 more source
Pharmacokinetics, Safety, and Dialyzability of Gadoquatrane in Patients With Impaired Renal Function: A Comprehensive Investigation Using Clinical Trial Data, Modeling and Simulation, and In Vitro Data. [PDF]
Fadini T +9 more
europepmc +1 more source
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu +17 more
wiley +1 more source
Exercise and Kidney Health: Core Curriculum 2026. [PDF]
Becerra LA, Mansour SG.
europepmc +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source

