Results 31 to 40 of about 225,712 (334)

Prevention of Protein Glycation by Natural Compounds [PDF]

open access: yes, 2015
Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz   +1 more
core   +2 more sources

Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla [PDF]

open access: yes, 2014
Background: Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetised blood as endogenous contrast ...
Delles, C.   +10 more
core   +3 more sources

Endothelial mineralocorticoid receptor ablation does not alter blood pressure, kidney function or renal vessel contractility. [PDF]

open access: yesPLoS ONE, 2018
Aldosterone blockade confers substantial cardiovascular and renal protection. The effects of aldosterone on mineralocorticoid receptors (MR) expressed in endothelial cells (EC) within the renal vasculature have not been delineated.
Sidsel B Laursen   +5 more
doaj   +1 more source

Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]

open access: yes, 2010
This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
core   +2 more sources

QiShenYiQi Pills, a Compound Chinese Medicine, Prevented Cisplatin Induced Acute Kidney Injury via Regulating Mitochondrial Function

open access: yesFrontiers in Physiology, 2017
Nephrotoxicity is a serious adverse effect of cisplatin chemotherapy that limits its clinical application, to deal with which no effective management is available so far.
Li Zhou   +41 more
doaj   +1 more source

Renal clearance of heparin-binding protein and elimination during renal replacement therapy: Studies in ICU patients and healthy volunteers.

open access: yesPLoS ONE, 2019
BackgroundHeparin-binding protein (HBP) is released by neutrophils upon activation, and elevated plasma levels are seen in inflammatory states like sepsis, shock, cardiac arrest, and burns. However, little is known about the elimination of HBP. We wanted
Line Samuelsson   +7 more
doaj   +1 more source

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

open access: yesBMC Medical Genomics, 2008
Background The P-glycoprotein, encoded by the ABCB1 gene, is expressed in human endothelial and mesangial cells, which contribute to control renal plasma flow and glomerular filtration rate.
Elston Robert C   +12 more
doaj   +1 more source

Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial. [PDF]

open access: yesPLoS ONE, 2017
The combination of weight excess and hypertension significantly contributes to cardiovascular risk and progressive kidney damage. An unfavorable renal hemodynamic profile is thought to contribute to this increased risk and may be ameliorated by direct ...
A J Kwakernaak   +10 more
doaj   +1 more source

Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]

open access: yes, 1993
The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
Eckardt, Kai-Uwe   +7 more
core   +2 more sources

Functional assessment of renal damage in children with primary vesicoureteral reflux

open access: yesFrontiers in Pediatrics
ObjectivesTo evaluate the renal function damage in children with primary vesicoureteral reflux (VUR).MethodsA total of 226 children with VUR (65 cases with left, 39 with right, and 122 cases with bilateral VUR) were screened.
Yaju Zhu, Yufeng Li, Jing Jin, Jiajia Ni
doaj   +1 more source

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