Prevention of Protein Glycation by Natural Compounds [PDF]
Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz +1 more
core +2 more sources
Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla [PDF]
Background: Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetised blood as endogenous contrast ...
Delles, C. +10 more
core +3 more sources
Endothelial mineralocorticoid receptor ablation does not alter blood pressure, kidney function or renal vessel contractility. [PDF]
Aldosterone blockade confers substantial cardiovascular and renal protection. The effects of aldosterone on mineralocorticoid receptors (MR) expressed in endothelial cells (EC) within the renal vasculature have not been delineated.
Sidsel B Laursen +5 more
doaj +1 more source
Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]
This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
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Nephrotoxicity is a serious adverse effect of cisplatin chemotherapy that limits its clinical application, to deal with which no effective management is available so far.
Li Zhou +41 more
doaj +1 more source
BackgroundHeparin-binding protein (HBP) is released by neutrophils upon activation, and elevated plasma levels are seen in inflammatory states like sepsis, shock, cardiac arrest, and burns. However, little is known about the elimination of HBP. We wanted
Line Samuelsson +7 more
doaj +1 more source
Association of
Background The P-glycoprotein, encoded by the ABCB1 gene, is expressed in human endothelial and mesangial cells, which contribute to control renal plasma flow and glomerular filtration rate.
Elston Robert C +12 more
doaj +1 more source
Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial. [PDF]
The combination of weight excess and hypertension significantly contributes to cardiovascular risk and progressive kidney damage. An unfavorable renal hemodynamic profile is thought to contribute to this increased risk and may be ameliorated by direct ...
A J Kwakernaak +10 more
doaj +1 more source
Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]
The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
Eckardt, Kai-Uwe +7 more
core +2 more sources
Functional assessment of renal damage in children with primary vesicoureteral reflux
ObjectivesTo evaluate the renal function damage in children with primary vesicoureteral reflux (VUR).MethodsA total of 226 children with VUR (65 cases with left, 39 with right, and 122 cases with bilateral VUR) were screened.
Yaju Zhu, Yufeng Li, Jing Jin, Jiajia Ni
doaj +1 more source

