Endothelial mineralocorticoid receptor ablation does not alter blood pressure, kidney function or renal vessel contractility. [PDF]
PLoS ONE, 2018 Aldosterone blockade confers substantial cardiovascular and renal protection. The effects of aldosterone on mineralocorticoid receptors (MR) expressed in endothelial cells (EC) within the renal vasculature have not been delineated.
Sidsel B Laursen +5 more
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PLoS ONE, 2019 BackgroundHeparin-binding protein (HBP) is released by neutrophils upon activation, and elevated plasma levels are seen in inflammatory states like sepsis, shock, cardiac arrest, and burns. However, little is known about the elimination of HBP. We wanted
Line Samuelsson +7 more
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Association of
BMC Medical Genomics, 2008 Background The P-glycoprotein, encoded by the ABCB1 gene, is expressed in human endothelial and mesangial cells, which contribute to control renal plasma flow and glomerular filtration rate.
Elston Robert C +12 more
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The effect of nisoldipine on apparent liver blood flow and effective renal plasma flow. [PDF]
British Journal of Clinical Pharmacology, 1985 The effects of the acute and continued administration of the calcium antagonist nisoldipine on hepatic and renal blood flow and on renal function were studied in nine normotensive volunteers. There were no significant changes in supine blood pressure or heart rate but acute administration significantly increased both apparent liver blood flow and ...
MEREDITH PA +3 more
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Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial [PDF]
, 2016 Aims/hypothesis: This study aimed to investigate the acute renal effects of the glucagon-like peptide-1 receptor agonist (GLP-1RA) exenatide in type 2 diabetes patients. Methods: We included overweight (BMI 25–40 kg/m2) men and postmenopausal women, aged
A. H. Jan Danser +8 more
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Functional assessment of renal damage in children with primary vesicoureteral reflux
Frontiers in PediatricsObjectivesTo evaluate the renal function damage in children with primary vesicoureteral reflux (VUR).MethodsA total of 226 children with VUR (65 cases with left, 39 with right, and 122 cases with bilateral VUR) were screened.
Yaju Zhu, Yufeng Li, Jing Jin, Jiajia Ni
doaj +1 more source
Protective effect of selenium on cisplatin induced nephrotoxicity: A double-blind controlled randomized clinical trial [PDF]
Journal of Nephropathology, 2013 Background: Renal injury is common following cisplatin infusion. Some agents have been used to attenuate cisplatin nephrotoxicity. However, except hydration, none of them has been proved to be effective.
Ali Ghorbani, Bita Omidvar, Abazar Parsi
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Nuclear medicine: investigation of renal function in small animal medicine [PDF]
, 2011 Kidney function investigations in veterinary medicine are traditionally based on blood analysis (blood urea nitrogen (BUN) and serum creatinine concentration) and / or urinalysis (urine specific gravity, protein-to-creatinine ratio or fractional ...
De Sadeleer, Carlos +7 more
core
Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]
, 1993 The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
Eckardt, Kai-Uwe +7 more
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Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source