Results 171 to 180 of about 3,043,757 (303)

Genetic diversity of Morato's Digger Toad, Proceratophrys moratoi: spatial structure, gene flow, effective size and the need for differential management strategies of populations. [PDF]

Genet Mol Biol, 2017
Arruda MP, Costa WP, Recco-Pimentel SM.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Magnetic resonance image enhancement by reducing receptors' effective size and enabling multiple channel acquisition. [PDF]

Annu Int Conf IEEE Eng Med Biol Soc, 2014
Yepes-Calderon F, Velasquez A, Lepore N, Beuf O.   +3 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Characterisation of linkage disequilibrium and subsequent estimation of effective population size in Thoroughbred horses using single nucleotide polymorphism markers

, 2010
M Vaudin, JA Woolliams, Vaudin, M., LJ Corbin, Woolliams, J.A., SC Blott, Blott, S.C., Swinburne, J.E., Bishop, S.C., Corbin, L.J., SC Bishop, JE Swinburne   +11 more
core   +1 more source

Temporal Variability in Effective Size ( N ̂ e ) Identifies Potential Sources of Discrepancies Between Mark Recapture and Close Kin Mark Recapture Estimates of Population Abundance. [PDF]

Mol Ecol Resour
Ruzzante DE, McCracken GR, Fraser DJ, MacMillan J, Buhariwalla C, Flemming JM.   +5 more
europepmc   +1 more source

Effective size of a wild salmonid population is greatly reduced by hatchery supplementation. [PDF]

Heredity (Edinb), 2012
Christie MR, Marine ML, French RA, Waples RS, Blouin MS.   +4 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Single nucleotide polymorphism profile for quantitative trait nucleotide in populations with small effective size and its impact on mapping and genomic predictions. [PDF]

Genetics
Pocrnic I, Lourenco D, Misztal I.
europepmc   +1 more source

The effective size of populations infected with cytoplasmic sex-ratio distorters. [PDF]

Genetics, 2010
Engelstädter J.
europepmc   +1 more source