Results 111 to 120 of about 1,505,358 (290)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Effective temperature concept evaluated in an active colloid mixture. [PDF]

Proc Natl Acad Sci U S A, 2017
Han M, Yan J, Granick S, Luijten E.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Effective Temperature and Universal Conductivity Scaling in Organic Semiconductors. [PDF]

Sci Rep, 2015
Abdalla H, van de Ruit K, Kemerink M.
europepmc   +1 more source

Effect of the splitting of the neutron and proton effective masses on the nuclear symmetry energy at finite temperatures

, 2011
Li Ou, Zhuxia Li, Yingxun Zhang, Min Liu
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Estimating the Atmospheric Parameters of Early-type Stars from the Chinese Space Station Telescope (CSST) Slitless Spectra Survey

The Astronomical Journal
The measurement of atmospheric parameters is fundamental for scientific research using stellar spectra. The Chinese Space Station Telescope (CSST), scheduled to be launched in 2024, will provide researchers with hundreds of millions of slitless spectra ...
JiaRui Rao, HaiLiang Chen, JianPing Xiong, LuQian Wang, YanJun Guo, JiaJia Li, Chao Liu, ZhanWen Han, XueFei Chen   +8 more
doaj   +1 more source

Heat production and error probability relation in Landauer reset at effective temperature. [PDF]

Sci Rep, 2016
Neri I, López-Suárez M.
europepmc   +1 more source

Effects of spatiotemporal O4 column densities and temperature-dependent O4 absorption cross-section on an aerosol effective height retrieval algorithm using the O4 air mass factor from the ozone monitoring instrument

, 2019
Wonei Choi, Hanlim Lee, Jhoon Kim, Jae-Yong Ryu, Sang Seo Park, Junsung Park, Hyeongwoo Kang   +6 more
openalex   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source