Results 121 to 130 of about 1,505,358 (290)
Anomalies, effective action and Hawking temperatures of a Schwarzschild black hole in the isotropic coordinates [PDF]
Shuang‐Qing Wu +2 more
openalex +1 more source
Effective Induction of Fertile Gametes in Oriental × Trumpet (OT) Lily by High Temperatures [PDF]
Yixuan Huang +6 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Determining the critical effective temperature and heat dispersal pattern in monopolar radiofrequency ablation using temperature-time integration. [PDF]
Tseng H +4 more
europepmc +1 more source
High-temperature expansion of the one-loop effective action induced by scalar and Dirac particles [PDF]
Igor Kalinichenko, Peter Kazinski
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Some like it cold: molecular emission and effective dust temperatures of dense cores in the Pipe Nebula [PDF]
Jan Forbrich +6 more
openalex +1 more source

