Results 171 to 180 of about 1,505,358 (290)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Using a neural network approach and starspots dependent models to predict effective temperatures and ages of young stars. [PDF]

PLoS One
Tarantino M, Prisinzano L, D'Angelo N, Damiani F, Adelfio G.   +4 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Probing the limits of effective temperature consistency in actively driven systems.

Soft Matter
Boriskovsky D, Goerlich R, Lindner B, Roichman Y.   +3 more
europepmc   +1 more source

Quantum refrigeration powered by noise in a superconducting circuit. [PDF]

Nat Commun
Sundelin S, Aamir MA, Kulkarni VM, Castillo-Moreno C, Gasparinetti S.   +4 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Establishing the phenological development stages of Sophora moorcroftiana using the BBCH scale. [PDF]

Sci Rep
Wan Y, Xin F, Bianba J, Guo X, Xie H, Zhang C, Liu J.   +6 more
europepmc   +1 more source

The Effective Potential of Electroweak Theory with Two Massless Higgs Doublets at Finite Temperature [PDF]

, 1994
Koichi Funakubo, A. Kakuto, Kazunori Takenaga   +2 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Influence of La Doping on the Magnetic Properties of the Two-Dimensional Spin-Gapped System SrCu₂(BO₃)₂. [PDF]

Inorg Chem
Šibav L, Knaflič T, King G, Jagličić Z, Koblar M, Povarov K, Zvyagin S, Arčon D, Dragomir M.   +8 more
europepmc   +1 more source