Results 71 to 80 of about 14,395,329 (289)

A Terrestrial Thermometer Using Carbonate Clumped Isotopes From Gar Scales

open access: yesGeochemistry, Geophysics, Geosystems
We present a new clumped isotope calibration relating temperature to the Δ47 composition of the bioapatite scales of gar fish (Lepisosteidae family). Modern gars live at
Katelyn E. Gray, Mark T. Brandon
doaj   +1 more source

TDEP: Temperature Dependent Effective Potentials

open access: yesJournal of Open Source Software
The Temperature Dependent Effective Potential (TDEP) method is a versatile and efficient approach to include temperature in ab initio materials simulations based on phonon ...
F. Knoop   +12 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Generalized N-Dimensional Effective Temperature for Cryogenic Systems in Accelerator Physics

open access: yesQuantum Beam Science
Investigations into the properties of generalized effective temperature are conducted across arbitrary dimensions. Maxwell–Boltzmann distribution is displayed for one, two, and three dimensions, with effective temperatures expressed for each dimension ...
Heetae Kim, Chang-Soo Park
doaj   +1 more source

Homemade Nucleic Acid Preservation Buffer Proves Effective in Preserving the Equine Faecal Microbiota over Time at Ambient Temperatures [PDF]

open access: gold, 2023
Ashley B. Ward   +9 more
openalex   +1 more source

Effective temperature of nonequilibrium dense matter in holography [PDF]

open access: yes, 2014
We study properties of effective temperature of non-equilibrium steady states by using the anti-de Sitter spacetime/conformal field theory (AdS/CFT) correspondence.
H. Hoshino, Shin-ichi Nakamura
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

The impact of the ozone effective temperature on satellite validation using the Dobson spectrophotometer network

open access: yes, 2016
. The main aim of the paper is to demonstrate an approach for post-processing of the Dobson spectrophotometers' total ozone columns (TOCs) in order to compensate for their known stratospheric effective temperature (Teff) dependency and its resulting ...
M. Koukouli   +7 more
semanticscholar   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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