Results 211 to 220 of about 2,384,733 (267)

Health economic evaluation of an interdisciplinary care pathway for older patients with vertigo, dizziness and balance disorders in primary care (MobilE-PHY2) - a cluster-randomised trial. [PDF]

Cost Eff Resour Alloc
Zimmer V, Horstmannshoff C, Bauer P, Borchers P, Scheibe S, Voigt K, Müller M, Köberlein-Neu J.   +7 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Management of Moderate-to-Highly Exuding Chronic Leg Ulcers With Superabsorbent Wound Dressings Versus Foams Dressings in Polish Settings: An Early-Stage Cost-Effectiveness Evaluation. [PDF]

Int J Nurs Pract
Veličković V, Serafin A, Mrozikiewicz-Rakowska B, Jawień A.   +3 more
europepmc   +1 more source

Cost-utility analysis of the wearable cardioverter defibrillator in high-risk post-myocardial infarction patients in the Spanish healthcare system. [PDF]

Front Cardiovasc Med
González Costello J, Exposito Garcia V, Moloney E, Kontogiannis V, Javanbakht M, Goromonzi F, Both B, Moreno R.   +7 more
europepmc   +1 more source

Cost-Effectiveness of Anticoagulation Treatment for Subclinical Device-Detected Atrial Fibrillation.

JAMA Netw Open
Winstén AK, Langén V, Airaksinen KEJ, Teppo K.   +3 more
europepmc   +1 more source

Triage effectiveness: a framework for quantifying the effect of emergency triage prioritization. [PDF]

BMC Med Res Methodol
Johansson A, Fodor V, Forberg JL, Ekwall A, Ekelund U.   +4 more
europepmc   +1 more source

Gynaecology Teaching Associates in Medical Education-A Scoping Review. [PDF]

Clin Teach
Kelly C, Bell E, Brown MEL, Stelling H.
europepmc   +1 more source

Economic evaluation of the second-line regimen of liposome irinotecan (II) combined with 5-FU/LV versus placebo combined with 5-FU/LV for locally advanced or metastatic pancreatic ductal adenocarcinoma in China. [PDF]

PLoS One
Huang J, Ye H, Lin J, Luo D, Huang P, Zheng X.   +5 more
europepmc   +1 more source