Results 101 to 110 of about 2,473,551 (267)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Translating evidence into primary care: Singapore’s 2025 national osteoporosis guideline and a multilevel framework for assessing guideline impact in mixed health systems

Family Medicine and Community Health
Objective Osteoporosis is a major contributor to morbidity and mortality worldwide, yet underdiagnosis and undertreatment remain pervasive across diverse health systems, including Singapore’s mixed public–private primary care landscape.
Kin Ming Chan, Cheryl Wei Yan Tan, Eu Leong Yong, Phyllis Kim, M Premikha, Valentina Ricci, Shu Jun Kan, Bernard Thong, Derek Shangxian Choong, Alexis Guat Cheng Ang, Andre Teck Huat Tan, Chee Kian Chew, Li Wei Cho, Thomas FJ King, Yang Chua, Joyce Suang Bee Koh, Victor Seah, Christine Ng, Kok Wai Kee, Kenneth Wei Qiang Choo, Shi Mun Chan, Murshitha Shereen Bte Sayed Majunoon, Jonathan Cheng Hsun Yeo, Anna Purani Raman Singarasoo, Cheuk Ying Chan   +24 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Abscopal Effects, Clastogenic Effects and Bystander Effects: 70 Years of Non-Targeted Effects of Radiation

Radiation Research
In vitro and in vivo observations accumulated over several decades have firmly shown that the biological effects of ionizing radiation can spread from irradiated cells/tissues to non-targeted cells/tissues. Redox-modulated intercellular communication mechanisms that include a role for secreted factors and gap junctions, can mediate these non-targeted ...
Lyng, Fiona M., Azzam, Edouard I.
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Content validity of the modified EQ-HWB-9 in a sample of Argentinean patients, informal caregivers, and members of the general public

Health and Quality of Life Outcomes
Background In response to the challenge of measuring the impact of health, social care, and informal caregiving on quality of life, the EuroQol Group developed the Experimental EuroQol Health and Wellbeing (EQ-HWB-9).
Maria Belizan, Natalí Ini, Fernando Argento, Michael Herdman, Clara Mukuria, Federico Augustovski   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Effect of Leadership Effectiveness on the Work Effectiveness of the Staffs

Journal of International Conference Proceedings, 2018
This research analyzed the effect of leadership effectiveness on employee effectiveness. The object of this research is Universitas Negeri Manado (UNIMA) as the Higher Education Institution. Research problem refers to data phenomenon in UNIMA. The fact presents that the staffs do not have maximum presence since they only go to work for 18 days per ...
openaire   +1 more source