Results 101 to 110 of about 4,197,911 (316)

CSO development effectiveness and the enabling environment : key messages for the Fourth High Level Forum on Aid Effectiveness [PDF]

open access: yes, 2011
As included in recommendations for strengthening the role of Civil Society Organizations in development processes: “Reaffirming the recognition of the full diversity of CSOs as independent development actors in their own right, CSOs play roles that ...
The Task Team on CSO Development Effectiveness and Enabling Environment
core  

Rapid synthesis: Assessing the effectiveness of virtual care for adults with mental health and/or addictions issues [PDF]

open access: yes, 2020
An in-depth synthesis of what is known based on the best available global research evidence (i.e., evidence syntheses) and local research evidence (i.e., single studies) as well as experiences from other countries and from Canadian provinces and ...
Evans, C   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

EFFECTS OF LEADERSHIP ROLES ON TEAM EFFECTIVENESS

open access: yesEge Akademik Bakis (Ege Academic Review), 2009
In this study we aim to explain the patterns of leadership roles for team effectiveness in non profit organizations compared to economic organizations. For this purpose, we studied three successful organization types, i.e the amateur sports clubs (football, basketball), theater companies and, regional folk groups.
DUYGULU, Ethem, ÇIRAKLAR, Nurcan
openaire   +5 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Process-Product Research: A Cornerstone in Educational Effectiveness Research

open access: yes, 2015
This article links the contribution of process-product studies in developing the theoretical framework of educational effectiveness by pointing out the importance of teacher behavior in the classroom.
Creemers, Bert, Kyriakides, Leonidas
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Effective civic education: An educational effectiveness model for explaining students' civic knowledge

open access: yes, 2011
In this study, a comprehensive educational effectiveness model is tested in relation to student's civic knowledge. Multilevel analysis was applied on the dataset of the IEA Civic Education Study (CIVED; Torney-Purta, Lehmann, Oswald, & Schulz, 2001 ...
Maslowski, Ralf   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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