Results 211 to 220 of about 2,473,551 (267)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

1-Year follow-up evaluation of TAK-003 dengue vaccine effectiveness against symptomatic disease and hospitalisation in adolescents during the 2024-2025 outbreak in São Paulo, Brazil: a test-negative case-control study. [PDF]

EClinicalMedicine
Krug Mareto L, Brumatti TS, Dias de Oliveira R, Vieira da Silva P, Ribeiro Dos Santos E, D'Agostini TL, Cardoso De Paula RA, Dean NE, Ko AI, Cummings DAT, Andrews JR, Hitchings MDT, Ranzani O, Croda J.   +13 more
europepmc   +1 more source

Towards Better Vaccines: Enhancing Benefits, Mitigating Risks. [PDF]

Vaccines (Basel)
See KC.
europepmc   +1 more source

Estimated benefits of providing on-demand pre-exposure prophylaxis options for cisgender women in South Africa: A modeling study. [PDF]

PLoS One
Stansfield SE, Moore M, Boily MC, Hughes JP, Donnell D, Bekker LG, Dimitrov DT.   +6 more
europepmc   +1 more source

Payers should cover COVID-19 vaccines for all ages and risk groups with no patient cost sharing. [PDF]

J Manag Care Spec Pharm
Hatton RC, Happe LE.
europepmc   +1 more source

Cost-Effectiveness of Community-Based Rehabilitation for People With Schizophrenia: A Secondary Analysis of a Cluster Randomized Trial.

JAMA Health Forum
Ding R, Zhao M, Wang Y, Xia Y, Guan X, Shi Z, He P.   +6 more
europepmc   +1 more source