Results 161 to 170 of about 5,134,083 (307)

Development Effectiveness Overview (DEO) 2011

, 2013
The Development Effectiveness Overview (DEO) is the IDB's annual corporate report that accounts for the effectiveness of its work, stating the results achieved with the implementation of the Bank's Development Effectiveness agenda.
Ibarrarán, Pablo, Martinez, Sebastian, Neret, Matilde, Meduña, Patricia, Pusterla, Fazia, Toda, Ichiro, Salazar, Lina, McCarthy, Nancy, Díaz, Luis, Winters, Paul, Linares, Ana María, Cruz-Aguayo, Yyannu, Mejía, Francisco, Sedlacek, Guilherme Luis, Azevedo, Viviane, Taboada, Bibiana, Cossens, Shakirah, Maffioli, Alessandro, Bertachini, Helio, Volpe Martincus, Christian, Manzano, Gádor, Rodríguez, César   +21 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cost-Effectiveness of Reducing HIV Infections Through Screening and Treating Alcohol Use and Depression in KwaZulu-Natal, South Africa: A Mathematical Modeling Study. [PDF]

J Acquir Immune Defic Syndr
Jeetoo M, Yeo YR, Charles DL, Moll AP, Shenoi SV, Morojele NK, Mbaya JK, Zama P, Gasa S, Francis JM, Braithwaite RS.   +10 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Factors Influencing Perceived Multidisciplinary Team Meeting Effectiveness in Teams Addressing Work-Related Respiratory Diseases: A Qualitative Study. [PDF]

J Multidiscip Healthc
Boezeman EJ, Zipfel N, Franklin SW, Verheijen NM, van Snippenburg R, Proper KI, Schaafsma FG.   +6 more
europepmc   +1 more source

Issues on Hedge Effectiveness Testing [PDF]

The starting point for risk management and hedging lies in understanding a corporation’s exposure to different risks. Hedging is vital for corporate risk management, involving reducing the exposure of the company to particular risks.
Petre, Mihaela Cosmina, Culiţă, Gica, Bunea-Bontaş, Cristina Aurora   +2 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Cost-effectiveness of herpes zoster vaccination in patients with rheumatoid arthritis. [PDF]

Rheumatology (Oxford)
Hagen G, Opheim AK, Overbo J, Aas E, Provan SA.   +4 more
europepmc   +1 more source