Results 251 to 260 of about 5,134,083 (307)

Community Perspectives on Effectiveness of Forest Governance and Conservation Behavior in Southwest Ethiopia: A Structural Equation Modelling and Qualitative Insights Approach. [PDF]

Environ Manage
Jebessa GM, Bekele AE, Tolera T.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Influenza Vaccine Effectiveness Against Mild and Severe Outcomes: A Comparison Study in Portugal. [PDF]

Influenza Other Respir Viruses
Mourao F, Gómez V, Soares P, Rodrigues AP, Dias CM, Machado A.   +5 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Editorial Comment From Dr. Kato to Post-Marketing Surveillance of the Safety and Effectiveness of Cabozantinib in Japanese Patients With Advanced Renal Cell Carcinoma. [PDF]

Int J Urol
Kato T, Matsukawa A, Nonomura N.
europepmc   +1 more source

Impact and cost-effectiveness of water, sanitation, hygiene, and health education interventions in the control and elimination of soil-transmitted helminthiasis: A scoping review. [PDF]

PLoS Negl Trop Dis
Okoyo C, Odhiambo M, Chepchieng G, Kioko J, Nyanchama B, Anjela M, Mwandawiro C, Minnery M.   +7 more
europepmc   +1 more source

Cost-effectiveness analysis of computer aided detection for tuberculosis in Ghana: A decision-analytic modeling study. [PDF]

PLoS One
Adusi-Poku Y, Idan JS, Mohammed A, Adu BW, Nakua EK, Owusu-Dabo E.   +5 more
europepmc   +1 more source

Comparative efficacy of dietary interventions and enteral nutrition in adults with ulcerative colitis: a network meta-analysis. [PDF]

Front Nutr
Wang T, Ji L, Sun C, Liu H, Li J, Hong Y.   +5 more
europepmc   +1 more source