Results 161 to 170 of about 4,197,911 (316)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Rapid evidence profile #63: Reviewing the effectiveness of cannabis on symptoms of select conditions
An overview of the best available research evidence from around the world (i.e., evidence syntheses) and local research evidence (i.e., single studies) and may include a scan of experiences from other countries and from Canadian provinces and territories,
Jaspal, A +3 more
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Assessing the Effectiveness of Agricultural Interventions
, 2016 The volume Assessing the Effectiveness of Agricultural Interventions is the Special Topic for the Development Effectiveness Overview 2008-2009. The Special Topic provides an in-depth analysis of what we know about the effectiveness of projects in one of ...
González, Mario +3 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Part 3, Section 2: Core Requirements,Section 2.5: Institution Effectiveness
, 2011 Compliance report statement of institutional effectiveness.The institution engages in ongoing, integrated, and institution-wide research-based planning and evaluation processes that (1) incorporate a systematic review of institutional mission, goals, and
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2018 Title from PDF caption (viewed on October 16, 2018).The Conservation Effectiveness Partnership includes Oregon Department of Agriculture, Oregon Department of Environmental Quality, USDA Natural Resources Conservation Service, Oregon Watershed ...
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Efficacy and effectiveness of long-acting monoclonal antibodies and vaccines against RSV: a systematic review and meta-analysis of studies from 2018 to 2025. [PDF]
EClinicalMedicineDu J, Li S, Hung IFN, Wu JT, Leung K.
europepmc +1 more source
Institutional Effectiveness Newsletter [Volume 2 Issue 2. Spring Semester 2012]
, 2012 Update on the work of the Office of Institutional Effectiveness (OIE).Complete College Georgia Overview--USG Data Warehouse Redesign--Spring 2012 Enrollment Snapshot--NSSE Update--Technology Advisory Committee Progress--PULLOUTS:Web Sightings; Did You ...
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source