Results 191 to 200 of about 5,703,320 (311)

Primary care effectiveness, multimorbidity, and hospital use in public and private health-care systems in Brazil: a cross-sectional analysis of data from the 2019-2021 Brazilian longitudinal study of aging. [PDF]

Lancet Reg Health Am
Oliveira GM, Nunes BP, Lam K, Lima-Costa MF, Torres JL, Macinko J, Moreira BS, Avelino-Silva TJ, Gonçalves VAD, Fortes-Filho SQ, de Castro TF, Batista SRR, Ferriolli E, Aliberti MJR.   +13 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Endogenous Cost-Effectiveness Analysis in Health Care Technology Adoption [PDF]

Increased health care spending has been argued to be largely due to technological change. Cost-effectiveness analysis is the main tool used by private and public third-party payers to prioritize adoption of the new technologies responsible for this ...
Tomas Philipson, Anupam Jena
core  

Cost-Effectiveness of Colorectal Cancer Screening Tests: Reply to Response. [PDF]

Cancer Epidemiol Biomarkers Prev
Estes C, Limburg PJ.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

A rational road to effectiveness attainment [PDF]

Operational effectiveness goes beyond efficiency while it incorporates exogenous variables, non-controllable by the service units. Effectiveness is a fundamental driver for the success of an operational unit within a competitive environment.
Zervopoulos, Panagiotis, Vargas, Francisco, Cheng, Gang   +2 more
core  

Immunisation and preventive measures against mpox in pregnant women and children: A scoping review. [PDF]

PLOS Glob Public Health
Rahman L, Eva FN, Ahsanuzzaman AKM, Monami S, Tabassum A, Nabi MH, Hawlader MDH.   +6 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Effectiveness Review: Pakistan Flood Response 2011/12

, 2012
The report presents the findings of an effectiveness review carried out on Oxfam's response to the 2011/12 floods in Pakistan that was undertaken through the application of Oxfam's Humanitarian Indicator Tool.
House, Sarah
core  

Cost-effectiveness of monotherapy and combination therapy for myopia control in Chinese children. [PDF]

J Glob Health
Wang J, Li X, He M, Song D, Zhang B, Du B, Wei R.   +6 more
europepmc   +1 more source