Results 201 to 210 of about 15,623 (268)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Breaking the Cycle of Echinococcosis: A Mathematical Modeling Approach. [PDF]

Trop Med Infect Dis
Lagos R, Gutiérrez-Jara JP, Cancino-Faure B, Lara-Díaz LY, Barradas I, González-Galeano A.   +5 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Migrastatic therapy as a potential game-changer in adaptive cancer treatment. [PDF]

Sci Rep
Schneider K, Spekking L, Azimi S, Peltanová B, Rösel D, Brown JS, Gatenby RA, Brábek J, Staňková K.   +8 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Improving cardiovascular population risk in primary care: protocol for the PROSPERA cluster-randomized controlled trial of a complex multilevel intervention

Bongaerts VAMC, Vos RC, Hageman SHJ, Redekop WK, Dorresteijn JAN, Numans ME, van Os HJA.   +6 more
europepmc   +1 more source

No differences in union rates between grafts for subtalar arthrodesis. [PDF]

EFORT Open Rev
Munoz MA, Khvesyuk M, Leroux V, Van Rooij F, Saffarini M, Rodaix C, Lalevee M.   +6 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Potential medical applicability of N-β-Ala and N-His dipeptidomimetics against breast cancer: short in vitro and in silico screening. [PDF]

Sci Rep
Chmielewska K, Budka J, Kozłowska-Tylingo K, Inkielewicz-Stepniak I, Dzierzbicka K.   +4 more
europepmc   +1 more source