Results 251 to 260 of about 8,184,686 (331)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Alcohol wipes are the most justifiably sustainable disinfection method for Goldmann tonometry. [PDF]

Eye (Lond)
Corbett JW, Sandhu SS, Gale J.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Sensitivity analysis enlightens effects of connectivity in a Neural Mass Model under Control-Target mode. [PDF]

PLoS Comput Biol
Vallet A, Blanco S, Chevallier C, Eustache F, Gautrais J, Grandpeix JY, Joly JL, Segobin S, Gagnepain P.   +8 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield. [PDF]

Front Endocrinol (Lausanne)
Li M, Chen W, Xue X.
europepmc   +1 more source

Osteomyelitis-relevant antibiotics at clinical concentrations show limited effectivity against acute and chronic intracellular <i>S. aureus</i> infections in osteocytes. [PDF]

Antimicrob Agents Chemother
Zelmer AR, Yang D, Gunn NJ, Solomon LB, Nelson R, Kidd SP, Richter K, Atkins GJ.   +7 more
europepmc   +1 more source

From Noise to Music: Reframing the Role of Context in Clinical Reasoning. [PDF]

J Gen Intern Med
Penner JC, Schuwirth L, Durning SJ.
europepmc   +1 more source