Results 231 to 240 of about 747,789 (299)

Immune remodeling in inflammatory bowel disease-associated colorectal cancer: Mechanisms and immunotherapeutic implications (Review). [PDF]

Int J Mol Med
Zhang T, Ren Z, Wang L, Man R, Wang L, Wang J, Cheng X, Peng J, Yu Y.   +8 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Evolutionary constraints and regulatory plasticity shape host specialization in the <i>Magnaporthe oryzae</i> species complex. [PDF]

Virulence
Hera MHR, Wu Q, Jibril SM, Li C, Wang Y.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Altered functional connectivity in inter-effector and effector-specific subregions of the primary motor cortex in Parkinson's disease. [PDF]

Neuroimage Clin
Li H, Chen W, Qi Y, Tang W, Zhang C, Fan H, Shu L, Lin L, Liu JR, Du X.   +9 more
europepmc   +1 more source

Engineering plant tandem kinase immune receptors expands effector recognition profiles. [PDF]

Sci Adv
Yu DS, Zdrzałek R, Katayama E, Akiyama H, Daykin L, Williams NJ, Goodridge I, Asuke S, Banfield MJ.   +8 more
europepmc   +1 more source

Acetylation enables a dual-targeting fungal effector to inhibit insect immunity and development. [PDF]

PLoS Pathog
Wang Y, Dong Y, Zhang Y, Wu S, Yu D, Yang G, Gao S, Yang Y, Dong S, Qin L, Huang B.   +10 more
europepmc   +1 more source

Sugar coating the invasion: how smut fungi sweet-talk maize cell wall guards. [PDF]

Plant Cell
Singla-Rastogi M.
europepmc   +1 more source