Results 141 to 150 of about 303,721 (255)

Bacterial effectors targeting the host ubiquitin system. [PDF]

Biochem Soc Trans
Eschger P, Hermanns T, Hofmann K.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Type III Effectors of <i>Pseudomonas syringae</i> pv. <i>tomato</i> DC3000: Molecular Mechanisms, Host Manipulation Networks, and Implications for Plant Disease Resistance. [PDF]

Life (Basel)
Zhong X, Huang J.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Type III effectors of symbiotic Rhizobia include diverse predicted transcriptional and post-transcriptional modulators. [PDF]

PLoS Biol
Teulet A, Schornack S.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Editorial: Secretomics: More Secrets to Unravel on Plant-Fungus Interactions

Frontiers in Plant Science, 2020
Jan Schirawski, Maryam Rafiqi, Dominique Job, Martijn Rep, Delphine Vincent   +4 more
doaj   +1 more source

Grapevine rust fungus Neophysopella tropicalis deploys protein effectors with plant immunity-suppressing activity during sequential stages of pathogenesis. [PDF]

Plant Cell Rep
Maia T, Ferro JV, Husein G, Bombardelli RGH, Monteiro-Vitorello CB.   +4 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

PIrates of the vacuole: phosphoinositide hijacking by T4SS intracellular pathogens. [PDF]

Microlife
Bonazzi M.
europepmc   +1 more source