Correction: Roles of SPI-2 T3SS effectors in virulence of <i>Salmonella</i> Choleraesuis and construction of a triple-gene mutant vaccine strain. [PDF]
Frontiers Production Office.
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Characterization of the Effector Candidate Repertoire in the Arbuscular Mycorrhizal Fungus <i>Rhizophagus irregularis</i>. [PDF]
Huang Y, Bi L, Zhu Y, Chen L, Yao R.
europepmc +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Strategies in immune subversion: How Yersinia pestis inhibits neutrophil responses. [PDF]
Sheneman KR, Lawrenz MB.
europepmc +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The type VI secretion system of Acinetobacter: mechanisms, biology and therapeutic potential. [PDF]
Jie J +5 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Functional Analysis Identifies Multiple Effectors of Candidatus Liberibacter Asiaticus Suppressing Plant Pattern-Triggered Immunity. [PDF]
He Z +7 more
europepmc +1 more source
Sugar flux and signaling in plant-microbe interactions
Bezrutczyk, M. +11 more
core +1 more source

