Results 1 to 10 of about 28,620 (203)

Effects of Ascent to High Altitude on Human Antimycobacterial Immunity [PDF]

open access: goldPLoS ONE, 2013
عدوى السل والمرض والوفيات كلها أقل شيوعًا عند الارتفاعات العالية من الارتفاعات المنخفضة وكان الصعود إلى الارتفاعات العالية موصى به تاريخيًا للعلاج. الآليات المناعية والفطرية الكامنة وراء الارتباط بين الارتفاع والسل غير واضحة. درسنا آثار الارتفاع على المتفطرات والمناعة المضادة للبكتيريا.
Sarah Eisen   +11 more
openalex   +9 more sources

Effects of Hypoxemia by Acute High-Altitude Exposure on Human Intestinal Flora and Metabolism [PDF]

open access: goldMicroorganisms, 2023
This study examined the effects of hypoxemia caused by acute high-altitude hypoxia (AHAH) exposure on the human intestinal flora and its metabolites. The changes in the intestinal flora, metabolism, and erythropoietin content in the AHAH population under altitude hypoxia conditions were comprehensively analyzed using 16S rRNA sequencing, metabonomics ...
Ping Qi   +4 more
openalex   +4 more sources

Impact of High-Altitude Hypoxia on Bone Defect Repair: A Review of Molecular Mechanisms and Therapeutic Implications

open access: yesFrontiers in Medicine, 2022
Reaching areas at altitudes over 2,500–3,000 m above sea level has become increasingly common due to commerce, military deployment, tourism, and entertainment.
Pei Chen   +5 more
doaj   +2 more sources

Introgressive Hybridization and Hypoxia Adaptation in High-Altitude Vertebrates

open access: yesFrontiers in Genetics, 2021
In natural populations of animals, a growing body of evidence suggests that introgressive hybridization may often serve as an important source of adaptive genetic variation.
Jay F. Storz, Anthony V. Signore
doaj   +2 more sources

High-Altitude Living Shapes the Skin Microbiome in Humans and Pigs

open access: yesFrontiers in Microbiology, 2017
While the skin microbiome has been shown to play important roles in health and disease in several species, the effects of altitude on the skin microbiome and how high-altitude skin microbiomes may be associated with health and disease states remains ...
Bo Zeng   +18 more
doaj   +2 more sources

Transcriptomic analysis of iPSC-derived endothelium reveals adaptations to high altitude hypoxia in energy metabolism and inflammation.

open access: yesPLoS Genetics
Tibetan adaptation to high-altitude hypoxia remains a classic example of Darwinian selection in humans. Amongst Tibetan populations, alleles in the EPAS1 gene - whose protein product, HIF-2α, is a central regulator of the hypoxia response - have ...
Olivia A Gray   +7 more
doaj   +2 more sources

Recent Observations of Human-induced Asymmetric Effects on Climate in Very High-Altitude Area

open access: goldPLoS ONE, 2014
Like urban heat islands (UHI), human-induced land degradation (HLD) is a phenomenon attributed to human activities, but this phenomenon occurs in non-urban areas. Although a large body of work has demonstrated that land-cover change influences local climate systems, little work has been done on separating the impact of HLD from naturally-occurring ...
Siqi Lu, Guifang Liu
openalex   +5 more sources

Adrenal, thyroid and gonadal axes are affected at high altitude

open access: yesEndocrine Connections, 2018
Humans cannot live at very high altitude for reasons, which are not completely understood. Since these reasons are not restricted to cardiorespiratory changes alone, changes in the endocrine system might also be involved.
M von Wolff   +7 more
doaj   +2 more sources

Effects of High Altitude on Lipid Components of Human Serum

open access: closedExperimental Biology and Medicine, 1968
SummarySerum lipid components were measured in eight male subjects exposed to an altitude of 14,000 feet for 14 days. Concentrations of total lipids rapidly decreased after the third day of exposure and a similar, although less pronounced decrease was observed in cholesterol levels.
George J. Klain, John P. Hannon
openalex   +3 more sources

Comparison of Management Outcomes of Acute Coronary Syndrome from High-Altitude Area and those Residing in Plains

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: The effects of high-altitude area (HAA) on humans are considerable, and among the various environmental risk factors, HAA is one which contributes to the incidence and prevalence of coronary artery disease. To date, no guidelines concerning
Anil Kumar, Manoj Kumar Yadav, Ran Singh
doaj   +2 more sources

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