Results 41 to 50 of about 46,784 (222)

A Mathematical Model for Suppression Subtractive Hybridization [PDF]

, 2002
Suppression subtractive hybridization (SSH) is frequently used to unearth differentially expressed genes on a whole-genome scale. Its versatility is based on combining cDNA library subtraction and normalization, which allows the isolation of sequences of
Beattie, Craig, Rink, Anette, Gadgil, Chetan, Hu, Wei-Shou   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

AlN-based BAW resonators with CNT electrodes for gravimetric biosensing

, 2011
Solidly mounted resonators (SMRs) with a top carbon nanotubes (CNTs) surface coating that doubles as an electrode and as a sensing layer have been fabricated.
García-Gancedo, Luis, Zhu, Z., G.M. Ashley, A.J. Flewitt, Milne, WI, Milne, W.I., Iborra, E., Luo, J.K., Garcia-Gancedo, L., Luo, J., Lu, JR, Lu, J.R., Iborra, Enrique, Milne, W. I., Lu, J. R., J. Olivares, E. Iborra, X.B. Zhao, Olivares, J, W.I. Milne, Zhu, Z, Iborra, E, Olivares Roza, Jimena, Flewitt, A. J., J.K. Luo, Flewitt, AJ, Luo, J. K., Luo, JK, Ashley, G.M., M. Clement, ,, J.R. Lu, Clement, M, Zhao, X. B., Flewitt, A.J., Clement Lorenzo, Marta, Ashley, GM, Zhao, XB, Olivares, J., Ashley, G. M., L. García-Gancedo, García-Gancedo, L, Zhao, X.B., Z. Zhu, Clement, M., Iborra Grau, Enrique, Lu, J. R.; id_orcid   +46 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The effects of drive cycle accessory load and degree of hybridization on fuel economy and emissions for hybrid electric buses

, 2010
Electronic Thesis or DissertationHybrid Electric Vehicles (HEVs) have gained much attention in recent years. This is mainly due to rising fuel prices and increasing environmental awareness.
Chen, Dennis
core   +1 more source

Enhanced photochromic efficiency of transparent and flexible nanocomposite films based on PEO-PPO-PEO and tungstate hybridization

, 2015
Nanocomposite hybrid films were prepared by depositing tungstate on PEO-PPO-PEO (EPE) templates under acidic conditions by a one-pot self-assembly sol-gel method.
Wang, C., Gao, Y. B., Wen, W. J., Zeng, X. P., Zhou, B. P., Hong, Y. Y.   +5 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Evaluarea gradului de sterilitate la floarea-soarelui

Agricultural Science, 2015
Cytoplasmic male sterility (CMS) is an indispensable and necessary tool for obtaining sunflower hybrids. The monitoring of seed quality regarding male sterility is an important element in achieving a high efficiency of hybridization based on CMS-Rf ...
ŞESTACOVA Tatiana , GÎSCĂ Ion , CUCEREAVÎI Aliona , TABĂRĂ Olesea   +3 more
doaj  

Efficiency of artificial hybridization in soybean during the summer depending on temperature and relative humidity

, 2015
Hybridization is an important improvement method used in the soybean culture. However, there is little information on the recommended relative moisture and air temperature degree for artificial pollination.
Cosme Damião Cruz, Fialho, Gustavo Sessa, Silvana da Costa Ferreira, Matsuo, Éder, Sediyama, Tuneo, Brommonschenkel, Sérgio Hermínio, Tuneo Sediyama, Sérgio Hermínio Brommonschenkel, Cruz, Cosme Damião, Ferreira, Silvana da Costa, Gustavo Sessa Fialho, Matsuo   +11 more
core   +1 more source